Table 3. Ventilation data recorded during baseline and hypercapnic challenge in C2 hemilesioned rats with moderate sparing of VM white matter and uninjured, control rats.

Values are means ± SE. The results of the two-way repeated measures ANOVA are provided for group (C2HS vs. sparing), condition (baseline vs. hypercapnia), and the interaction term. Ti, inspiratory duration; Te, expiratory duration; VT/TI, mean inspiratory airflow rate; TI:TTOT, ratio of inspiratory duration to total breath duration; PIF, peak inspiratory airflow rate; PEF, peak expiratory airflow rate

	Condition	Control	Moderate Lesion	P-value group	P-value condition	P-value interaction
Ti (sec)	Baseline Hypercapnia	0.28±0.01 0.15±0.01	0.27±0.01 0.18±0.01	0.673	<0.001	0.022
Te (sec)	Baseline Hypercapnia	0.70±0.04 0.22±0.01	0.55±0.03 0.24±0.01	0.042	<0.001	0.005
VT/TI (ml/sec)	Baseline Hypercapnia	8.6±0.5 25.9±1.4	8.3±0.4 23.2±1.0	0.228	<0.001	0.199
TI:TTOT	Baseline Hypercapnia	0.29±0.02 0.41±0.01	0.33±0.01 0.42±0.01	0.010	<0.001	0.127
PIF (ml/sec)	Baseline Hypercapnia	14.0±0.9 37.8±2.2	13.3±0.6 31.7±1.5	0.050	<0.001	0.036
PEF (ml/sec)	Baseline Hypercapnia	8.4±0.3 30.6±1.5	9.6±0.5 29.1±1.1	0.874	<0.001	0.093