Table 3. IC50 Values for Mce6, SOS, and HPMA Copolymer−Mce6/−SOS Conjugates against OVCAR-3 Cells.
drug | incubation time (days) |
IC50 or Dm (μM)a |
---|---|---|
Mce6 | 1 | 3.34 ± 0.43 |
P-GFLG-Mce6 | 1 | 12.5 ± 1.06 |
P-(GFLG-Mce6)-Fab′ | 1 | 1.35 ± 0.10 |
SOS | 4 | 2.02 ± 0.17 |
P-GFLG-SOS | 4 | 32.9 ± 4.94 |
P-(GFLG-SOS)-Fab′ | 4 | 43.8 ± 2.90 |
Dm is the median-effect dose that inhibits the cell growth by 50%. IC50 and Dm values are the means ± SEM (n = 6 in single experiment).