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. 2008 Aug 27;5(5):696–709. doi: 10.1021/mp800006e

Table 3. IC50 Values for Mce6, SOS, and HPMA Copolymer−Mce6/−SOS Conjugates against OVCAR-3 Cells.

drug incubation
time (days)
IC50 or Dm
(μM)a
Mce6 1 3.34 ± 0.43
P-GFLG-Mce6 1 12.5 ± 1.06
P-(GFLG-Mce6)-Fab′ 1 1.35 ± 0.10
SOS 4 2.02 ± 0.17
P-GFLG-SOS 4 32.9 ± 4.94
P-(GFLG-SOS)-Fab′ 4 43.8 ± 2.90
a

Dm is the median-effect dose that inhibits the cell growth by 50%. IC50 and Dm values are the means ± SEM (n = 6 in single experiment).