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Effects of IgG depletion on the ability of sera to modulate CHIPS binding to the human C5a receptor
| Serum (effect on CHIPS binding) | Change in CHIPS binding (%)a |
|
|---|---|---|
| Untreated Serum | IgG-depleted serum | |
| 21 (inhibiting) | 13 | 41 |
| 29 (inhibiting) | 3 | 67 |
| 30 (inhibiting) | 49 | 71 |
| 31 (inhibiting) | 12 | 83 |
| 17 (enhancing) | 386 | 121 |
| 18 (enhancing) | 214 | 100 |
| 27 (inhibiting) | 4 | 76 |
Change in CHIPS binding relative to control (=100%) at 1/2 dilution of serum.
