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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: J Hepatol. 2008 May 20;49(4):581–588. doi: 10.1016/j.jhep.2008.03.032

Table 3.

Gene loci and related MS. Nine of the 18 MS tested were significantly associated with HCC recurrence.

Locus Gene Microsatellite GenBank % non-informative % AI overall % AI Milan=no %AI Milan=yes %AI recur=yes %AI recur=no p value
1p34.2 L-MYC MYCL 5NT M19720 24.3% 34.0% 57.7% 11.1% 75.0% 9.1% <0.0001
1p36.21 ** D1S407 L18040 28.6% 36.0% 53.6% 13.6% 60.0% 20.0% 0.0016
3p24.3 OGG! D3S2303 L17972 28.6% 34.0% 44.0% 24.0% 60.0% 22.9% 0.0085
3p26.3 OGG1 D3S1539 L16393 21.4% 29.1% 36.7% 20.0% 52.4% 14.7% 0.0026
5q21 MCC MCC E10 M62397 37.1% 11.4% 14.3% 8.7% 21.4% 6.7% 0.2
5q23.1 APC D5S592 L16423 24.3% 34.0% 40.0% 28.5% 38.9% 31.4% 0.57
5q23.2 APC D5S615 L18737 24.3% 24.5% 31.0% 16.7% 36.8% 17.7% 0.09
7q22.3 MET D7S1530 L30387 22.9% 22.2% 16.0% 27.6% 16.7% 25.0% 0.46
8q24.3 C-MYC D8S373 L16320 25.7% 23.1% 33.3% 14.3% 41.2% 14.3% 0.024
9p21.1 CDKN2A D9S251 L18726 25.7% 17.3% 24.0% 11.1% 25.0% 13.9% 0.29
9p23 CDKN2A D9S254 L18040 17.1% 31.0% 43.3% 17.9% 42.9% 24.3% 0.12
10q23.33 PTEN D10S520 L16357 28.6% 20.0% 20.8% 19.2% 35.7% 13.9% 0.06
10q23.32 PTEN D10S1173 L30341 25.7% 30.8% 30.8% 30.7% 42.1% 24.2% 0.14
17p12 TP53 D17S1289 G09615 17.1% 10.3% 15.2% 4.0% 22.7% 2.8% 0.0031
17p12 TP53 D17S974 G07961 22.9% 20.4% 33.3% 7.4% 40.0% 8.8% 0.0006
17p13.1 TP53 TP53 L1 M13121 38.6% 11.6% 11.1% 12.0% 11.1% 11.8% 0.98
17q25.1 ** D17S1163 L30445 18.6% 14.0% 24.1% 3.6% 31.6% 5.3% 0.0022
18q21.33 DCC D18S814 L17776 34.3% 47.8% 72.7% 25.0% 80.0% 32.3% 0.0022
**

no known tumor-related gene at these loci