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. Author manuscript; available in PMC: 2009 Feb 24.
Published in final edited form as: J Am Coll Cardiol. 2006 Jan 4;47(2):345–353. doi: 10.1016/j.jacc.2005.09.025

Table 3.

Parameters That Significantly Contributed to NT-proBNP Values in Multivariate Analysis

Parameters Included
in the Model
Regression Coefficient Standard Error Partial r2 p Value
Normal population
 Female gender 1.098 0.082 0.296 < 0.0001
 Age 0.041 0.005 0.077 < 0.0001
 LA volume index 0.029 0.007 0.025 < 0.0001
 LV dimension index 0.373 0.146 0.009 0.0109
 Heart rate −0.009 0.004 0.005 0.0223
Total population
 Age 0.052 0.003 0.296 < 0.0001
 LA volume index 0.041 0.003 0.077 < 0.0001
 Female gender 1.176 0.076 0.071 < 0.0001
 Serum creatinine 1.167 0.159 0.018 < 0.0001
 LV dimension index 0.441 0.107 0.016 < 0.0001
 GFR 0.004 0.001 0.003 0.0025
 BMI −0.029 0.008 0.003 < 0.0001
 LV mass 0.002 0.000 0.003 0.0012
Abnormal population
 Age 0.047 0.004 0.276 < 0.0001
 LA volume index 0.041 0.004 0.074 < 0.0001
 Female gender 1.057 0.095 0.055 < 0.0001
 Serum creatinine 1.409 0.184 0.036 < 0.0001
 LV dimension index 0.385 0.132 0.019 0.0035
 BMI −0.035 0.009 0.006 0.0002
 GFR 0.004 0.002 0.004 0.0089
 LV mass 0.003 0.000 0.003 0.0026

Parameters included in the model that were not significant in any of the subgroups were systolic and diastolic blood pressure. The NT-proBNP values were log-transformed for this analysis.

BMI = body mass index; GFR = glomerular filtration rate; LA = left atrial; LV = left ventricular; NT-proBNP = amino-terminal pro-B-type natriuretic peptide.