Table 3.
Parameters That Significantly Contributed to NT-proBNP Values in Multivariate Analysis
Parameters Included in the Model |
Regression Coefficient | Standard Error | Partial r2 | p Value |
---|---|---|---|---|
Normal population | ||||
Female gender | 1.098 | 0.082 | 0.296 | < 0.0001 |
Age | 0.041 | 0.005 | 0.077 | < 0.0001 |
LA volume index | 0.029 | 0.007 | 0.025 | < 0.0001 |
LV dimension index | 0.373 | 0.146 | 0.009 | 0.0109 |
Heart rate | −0.009 | 0.004 | 0.005 | 0.0223 |
Total population | ||||
Age | 0.052 | 0.003 | 0.296 | < 0.0001 |
LA volume index | 0.041 | 0.003 | 0.077 | < 0.0001 |
Female gender | 1.176 | 0.076 | 0.071 | < 0.0001 |
Serum creatinine | 1.167 | 0.159 | 0.018 | < 0.0001 |
LV dimension index | 0.441 | 0.107 | 0.016 | < 0.0001 |
GFR | 0.004 | 0.001 | 0.003 | 0.0025 |
BMI | −0.029 | 0.008 | 0.003 | < 0.0001 |
LV mass | 0.002 | 0.000 | 0.003 | 0.0012 |
Abnormal population | ||||
Age | 0.047 | 0.004 | 0.276 | < 0.0001 |
LA volume index | 0.041 | 0.004 | 0.074 | < 0.0001 |
Female gender | 1.057 | 0.095 | 0.055 | < 0.0001 |
Serum creatinine | 1.409 | 0.184 | 0.036 | < 0.0001 |
LV dimension index | 0.385 | 0.132 | 0.019 | 0.0035 |
BMI | −0.035 | 0.009 | 0.006 | 0.0002 |
GFR | 0.004 | 0.002 | 0.004 | 0.0089 |
LV mass | 0.003 | 0.000 | 0.003 | 0.0026 |
Parameters included in the model that were not significant in any of the subgroups were systolic and diastolic blood pressure. The NT-proBNP values were log-transformed for this analysis.
BMI = body mass index; GFR = glomerular filtration rate; LA = left atrial; LV = left ventricular; NT-proBNP = amino-terminal pro-B-type natriuretic peptide.