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. Author manuscript; available in PMC: 2009 Feb 24.
Published in final edited form as: J Am Coll Cardiol. 2006 Jan 4;47(2):345–353. doi: 10.1016/j.jacc.2005.09.025

Table 6.

NT-proBNP Cutpoints, Sensitivity, and Specificity for Age and Gender Strata for the Detection of an Ejection Fraction ≤ 40%

Men
Women
Age NT-proBNP Sens Spec NT-proBNP Sens Spec
45–54 yrs 108 100 96 ND ND ND
55–64 yrs 234 100 94 246 100 90
65–74 yrs 462 91 94 773 100 98
≥75 yrs 1,024 89 84 879 75 86

Cutpoints are based on optimal discriminatory value obtained from stratum-specific ROC curves.

ND = not determined; NT-proBNP = amino-terminal pro-B-type natriuretic peptide; Sens = sensitivity; Spec = specificity.