Table 7.
Test Characteristics*
| Prevalence | NT-proBNP Partition Value | Sensitivity % |
Specificity % |
% Screened Needing Echocardiogram | % Echocardiograms That Are Negative | % With Missed Disease | +LR | −LR | Odds Ratio | |
|---|---|---|---|---|---|---|---|---|---|---|
| Unadjusted | ||||||||||
| Population | 2.0 | 228 | 86.5 | 86.0 | 15.4 | 88.9 | 13.5 | 6.2 | 0.16 | 39 |
| Male only | 3.2 | 209 | 86.2 | 87.4 | 15.0 | 81.6 | 13.8 | 6.8 | 0.16 | 43 |
| Female only | 0.8 | 372 | 83.3 | 83.3 | 17.3 | 96.0 | 16.7 | 5.0 | 0.20 | 25 |
| Adjusted | ||||||||||
| Population | 2.0 | Variable | 91.9 | 93.6 | 8.1 | 77.5 | 8.1 | 14.4 | 0.09 | 166 |
| Male only | 3.2 | Variable | 93.1 | 93.4 | 9.4 | 68.2 | 6.9 | 14.1 | 0.07 | 190 |
| Female only | 0.8 | Variable | 87.5 | 93.8 | 6.9 | 89.4 | 12.5 | 14.1 | 0.13 | 106 |
*
Characteristics for the total population, male patients only, and female patients only for strategies based on a single NT-proBNP cutpoint (unadjusted) or a variable age- and gender-adjusted NT-proBNP cutpoint. +LR = positive likelihood ratio; −LR = negative likelihood ratio; NT-proBNP = amino-terminal pro-B-type natriuretic peptide.