Macroscopic haematuria
Microscopic haematuria in patients over 50 years and those at high risk
Any swelling in the body of the testis
Palpable renal masses
Solid renal masses found on imaging
A high PSA (> 20 ng/ml) in men with a clinically malignant prostate or bone pain
An elevated age-specific PSA in men with a 10-year life expectancy
Any suspected penile cancer
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