Table 1.

Percentage of optimal pseudocount existence

Sample size	Matrix-based			Sequence-based
	ED (%)	COS (%)	TVD (%)	ED (%)	COS (%)	TVD (%)	SRC (%)
10	99.2	100.0	28.7	100.0	95.9	54.1	45.9
20	99.2	100.0	16.4	99.2	95.9	26.2	34.4
30	100.0	100.0	13.1	100.0	94.3	13.1	20.5
40	100.0	100.0	9.0	99.2	95.1	11.5	14.8
50	100.0	99.2	10.7	99.2	95.1	9.0	5.7