Table 1.
Conductance, duration and occurrence of blocks of the αHL pore produced by Ctrl-2 and TBA in various ion solutions (+100 mV)
| DNA | Ion | Short block |
Long Block |
|||
|---|---|---|---|---|---|---|
| g (pS) | τ (μs) | f (s−1) | G (pS) | τ (s) | ||
| Ctrl-2 | Li+ | 53 ± 4 | 450 ± 206 | 29 | ||
| TBA | Li+ | 47 ± 6 | 629 ± 80 | 12 | 355 ± 35 | 15 ± 4 |
| Ctrl-2 | Na+ | 100 ± 12 | 404 ± 95 | 23 | ||
| TBA | Na+ | 89 ± 8 | 597 ± 100 | 7.0 | 438 ± 31 | 0.35 ± 0.14 |
| Ctrl-2 | K+ | 110 ± 27 | 361 ± 103 | 18 | ||
| TBA | K+ | 84 ± 14 | 322 ± 61 | 2.3 | 599 ± 18 | 15 ± 3 |
| Ctrl-2 | NH4+ | 145 ± 11 | 429 ± 91 | 25 | ||
| TBA | NH4+ | 107 ± 16 | 457 ± 65 | 4.5 | 627 ± 18 | 4.0 ± 0.8 |
| Ctrl-2 | Cs+ | 88 ± 30 | 349 ± 111 | 22 | ||
| TBA | Cs+ | 43 ± 9 | 279 ± 51 | 5.7 | 545 ± 25 | 12 ± 1.3 |
| Ctrl-2 | Ba2+ | 50 ± 9 | 1280 ± 220 | 3.3 | ||
| TBA | Ba2+ | 17 ± 7 | 1490 ± 330 | 0.64 | 807 ± 23 | 17 ± 4.4 |
| Ctrl-2 | Mg2+ | 42 ± 18 | 5700 ± 1500 | 1.3 | ||
| TBA | Mg2+ | 13 ± 8 | 4100 ± 390 | 0.9 | ||
| Ctrl-2 | Ca2+ | 55 ± 21 | 4200 ± 500 | 2.5 | ||
| TBA | Ca2+ | 30 ± 16 | 3400 ± 450 | 1.2 | ||