Table 2. Effectiveness of Hib conjugate vaccine against meningitis outcomes among children aged 0–59 months, Uganda, 2001–2006.
| Vaccine dosesa | Vaccine effectiveness against meningitis outcomeb
% (95% confidence interval) |
||
|---|---|---|---|
| Confirmed Hib | Purulentc CSF of unknown cause | CSF with 20–99 WBC/µl of unknown cause | |
| 1 | 63 (0–86) | 60 (21–80) | 38 (-54–75) |
| 2 | 93 (42–99) | 36 (-10–63) | 66 (-10–90) |
| 3 | 94 (48–99) | 68 (46–81) | 15 (-51–52) |
| 1 or more | 65 (41–79) | 38 (23–50) | 31 (3–51) |
| 2 or more | 93 (69–99) | 53 (11–68) | 35 (-11–62) |
CSF, cerebrospinal fluid; Hib, Haemophilus influenzae type b; WBC, white blood cells. a Values for 1, 2, 3 and 2+ vaccine doses were documented in immunization cards; values for 1+ doses also included a verbal report. b All vaccine effectiveness estimates adjusted for age. c CSF that was visually cloudy or had ≥ 100 white blood cells (WBC)/µl.