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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Biochim Biophys Acta. 2009 Jan 2;1793(3):561–571. doi: 10.1016/j.bbamcr.2008.12.016

Fig. 4.

Fig. 4

CASP10-mediated cell death requires proteolytic activation. A, western-blot analysis of protein crude extracts from a caspase-10 expressing strain. Ponceau red staining of the blot was used as protein loading control. B, schematic representation of the proteolytic activation of caspase-10. The residues involved in either activation or catalysis are indicated with arrows. C, plate assay of S. cerevisiae strains expressing different CASP10 alelles. D, growth curves of S. cerevisiae strains expressing different CASP10 alelles.