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An antigen is processed by an antigen-presenting cell (APC) and presented in the form of a peptide in the context of an HLA molecule. According to our hypothesis, both HLA-DRB1*0301 and HLA-DRB3*0101 molecules can present identical peptides, and be recognized preferentially by T-cell receptor AV2S3+ CD4+ T lymphocytes. Ag = antigen.
