TABLE 3.

OVERVIEW OF SELECTED INSTRUMENTS THAT ASSESS SIGNS AND SYMPTOMS IN CYSTIC FIBROSIS

	Smith	RSSQ	CFQ-R	SGRQ
Signs and symptoms (new or increased)
Pulmonary signs and symptoms
Increased dypsnea w/exertion		X		X
Decreased exercise tolerance	X	X	X	X
Increased work of breath	X		X
Cough	X	X	X	X
Day cough			X
Night cough			X
Wet or congested cough
Chest congestion		X	X
Frequency of cough		X	X
Cough up mucus			X	X
Wheezing			X	X
Hemoptysis/coughing up blood		X
Sputum volume	X	X	X
Change in sputum appearance	X	X
Change in sputum color			X
Change in sputum consistency
Increased respiratory rate	X
Decreased lung function	X
Upper respiratory tract symptoms
Sore throat/runny nose
Sinus pain/tenderness		X
Change in sinus discharge		X
Constitutional and GI signs and symptoms
Malaise/fatigue/lethargy		X	X
Abdominal pain			X
Decreased appetite	X	X	X
Fever (> 38° C)		X
Weight change	X	X	X
Function
Absenteeism		X	X	X
Sports/lifting/running/walking	X		X	X
Feeling
Tired/mad/grouchy/worried/sad			X	X
Psychosocial			X	X

Definition of abbreviations: CFQ-R = Cystic Fibrosis Questionnaire–Revised; GI = gastrointestinal; RSSQ = Respiratory and Systemic Symptoms Questionnaire; SGRQ = St. George's Respiratory Questionnaire; Smith = Smith and colleagues' acute change score (62).