TABLE 1.
ALLELIC FREQUENCIES OF SINGLE NUCLEOTIDE POLYMORPHISMS IN THE IL4 GENE IN FOUR ETHNIC GROUPS (WEST AFRICAN, AFRICAN AMERICAN, BRAZILIAN, EUROPEAN)
| Minor Allelic Frequencies (%)
|
|||||
|---|---|---|---|---|---|
| IL4 Marker | Allele | YRI* | GRAAD† | Brazil‡ | CEU§ |
| rs2070874 | C/T | 46.7 | 44.8 | 39.9 | 15.8 |
| rs2227284 | C/A | 99.2 | 44.4 | 40.6 | 27.1 |
| rs2243267 | G/C | 37.5 | 36.5 | 32.9 | 16.7 |
| rs2243270 | A/G | 77.5 | 37.0 | 37.7 | 15.5 |
| rs2243291 | C/G | 25.8 | 43.0 | 41.2 | 82.8 |
| rs734244 | A/G | 53.3 | 42.5 | 48.0 | 84.2 |
YRI, Yoruba people in Ibadan, Nigeria; allelic frequencies based on founders from 30 parent-and-adult-child trios participating in the International HapMap Project.
GRAAD, the consortium on Genomic Research on Asthma in the African Diaspora; allelic frequencies based on 306 healthy control subjects participating in an asthma genetics study in the Baltimore–Washington, DC, metropolitan area (unpublished data).
Allelic frequencies based on 205 founders participating in a family-based study on susceptibility to asthma and schistosomiasis in the Conde district, Bahia, Brazil (unpublished data).
CEU, European Americans from Utah, from the Centre d'Etude du Polymorphisme Humain collection; allelic frequencies based on founders from 30 parent-and-adult-child trios participating in the International HapMap Project.