TABLE 3.
GENES RESPONSIVE TO LIPOPOLYSACCHARIDE AND BLEOMYCIN*
| Symbol | Bleomycin/Saline (C57) | Lipopolysaccharide/Unexposed | Name |
|---|---|---|---|
| Saa3 | 9.84 | 82.66 | Serum amyloid A 3 |
| Ccl8 | 8.99 | 3.14 | Chemokine (C-C motif) ligand 8 |
| Cxcl9 | 6.30 | 9.29 | Chemokine (C-X-C motif) ligand 9 |
| Ccl17 | 5.79 | 1.84 | Chemokine (C-C motif) ligand 17 |
| Cxcl10 | 5.77 | 38.16 | Chemokine (C-X-C motif) ligand 10 |
| Adfp | 0.21 | 2.17 | Adipose differentiation related protein |
| Socs3 | 4.24 | 3.89 | Suppressor of cytokine signaling 3 |
| Tnc† | 4.03 | 5.76 | Tenascin C |
| Ccl9 | 3.95 | 7.85 | Chemokine (C-C motif) ligand 9 |
| Ccl12 | 3.83 | 2.93 | Chemokine (C-C motif) ligand 12 |
| Hc | 0.27 | 1.96 | Hemolytic complement |
| Mt1 | 3.63 | 3.25 | Metallothionein 1 |
| C1qb | 3.60 | 1.54 | Complement component 1, q subcomponent, beta polypeptide |
| C330016K18Rik | 0.28 | 0.61 | RIKEN cDNA C330016K18 gene |
| Rhou | 3.55 | 2.42 | ras homolog gene family, member U |
| Ch25h | 3.53 | 3.20 | Cholesterol 25-hydroxylase |
| Msr1 | 3.46 | 3.11 | Macrophage scavenger receptor 1 |
| Gadd45g | 3.43 | 1.63 | Growth arrest and DNA-damage–inducible 45 gamma |
| Fcer2a | 0.30 | 1.89 | Fc receptor, IgE, low affinity II, alpha polypeptide |
| Cspg2 | 3.32 | 2.27 | Chondroitin sulfate proteoglycan 2 |
| Pon1 | 0.30 | 0.29 | Paraoxonase 1 |
| 2410015N17Rik | 3.23 | 0.65 | RIKEN cDNA 2410015N17 gene |
| Cdkn1a | 3.08 | 1.88 | Cyclin-dependent kinase inhibitor 1A (P21) |
| Slc23a1 | 0.35 | 0.67 | Solute carrier family 23 (nucleobase transporters), member 1 |
| Mt2 | 2.86 | 5.90 | Metallothionein 2 |
| Ifit1 | 2.74 | 3.03 | Interferon-induced protein with tetratricopeptide repeats 1 |
| Cyp7b1 | 2.72 | 1.96 | Cytochrome P450, family 7, subfamily b, polypeptide 1 |
| Fcgr2b | 2.67 | 4.14 | Fc receptor, IgG, low affinity IIb |
| Gp49a /// Lilrb4 | 2.58 | 3.29 | Glycoprotein 49 A /// leukocyte immunoglobulin-like receptor, subfamily B, member 4 |
| Ccr1 | 2.50 | 6.47 | Chemokine (C-C motif) receptor 1 |
| G1p2 | 2.47 | 1.36 | Interferon, alpha-inducible protein |
| Col3a1† | 2.46 | 3.05 | Procollagen, type III, alpha 1 |
| Irf7 | 2.38 | 1.90 | Interferon regulatory factor 7 |
| Junb | 2.18 | 1.59 | Jun-B oncogene |
| Ptger4 | 2.15 | 1.85 | Prostaglandin E receptor 4 (subtype EP4) |
| Gclc | 2.10 | 2.55 | Glutamate-cysteine ligase, catalytic subunit |
| Akr1b8 | 2.03 | 1.86 | Aldo-keto reductase family 1, member B8 |
| S100a8 | 2.00 | 9.14 | S100 calcium binding protein A8 (calgranulin A) |
| Anxa1 | 1.99 | 3.18 | Annexin A1 |
| Osmr | 1.95 | 2.75 | Oncostatin M receptor |
| Cyp2a4 /// Cyp2a5 | 0.53 | 0.27 | Cytochrome P450, family 2, subfamily a, polypeptide 4 /// cytochrome P450, family 2, subfamily a, polypeptide 5 |
| Il18bp | 1.86 | 2.70 | IL-18 binding protein |
| Gfra1 | 0.55 | 0.39 | Glial cell line–derived neurotrophic factor family receptor alpha 1 |
| Plaur | 1.79 | 1.67 | Urokinase plasminogen activator receptor |
| Cebpd | 1.73 | 2.81 | CCAAT/enhancer binding protein, delta |
| Il4ra | 1.71 | 2.31 | IL-4 receptor, alpha |
| Ldh2 | 0.59 | 0.54 | Lactate dehydrogenase 2, B chain |
| Casp11 | 1.71 | 1.83 | Caspase 11, apoptosis-related cysteine protease |
| AI607873 | 1.64 | 3.17 | Expressed sequence AI607873 |