Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2009 Aug 26.

Published in final edited form as: Vaccine. 2008 Jul 18;26(36):4676–4685. doi: 10.1016/j.vaccine.2008.06.099

Fig. 1 — The effect of c-di-GMP pretreatment on S. pneumoniae Xen10 infection. Luminescence was quantified in the thorax of individual mice given c-di-GMP, cGMP or PBS before S. pneumoniae Xen10 infection at: (a) 1, 2.5 and 4 h, (b) 18, 24, 40 and 48 h and (c) 1, 4, 18, 24, 40 and 48 h post challenge. Mean (±SEM) luminescences were calculated for each group at each time point. *P<0.01 vs. PBS control group by Student’s t-test. (d–f) Luminescence images taken at 48 h post Xen10 challenge. Two mice within the cGMP group died as a result of infection at 24–42 h. In all cases n=5 mice per group. Results are representative of 2 separate experiments.

Fig. 1 — The effect of c-di-GMP pretreatment on S. pneumoniae Xen10 infection. Luminescence was quantified in the thorax of individual mice given c-di-GMP, cGMP or PBS before S. pneumoniae Xen10 infection at: (a) 1, 2.5 and 4 h, (b) 18, 24, 40 and 48 h and (c) 1, 4, 18, 24, 40 and 48 h post challenge. Mean (±SEM) luminescences were calculated for each group at each time point. *P<0.01 vs. PBS control group by Student’s t-test. (d–f) Luminescence images taken at 48 h post Xen10 challenge. Two mice within the cGMP group died as a result of infection at 24–42 h. In all cases n=5 mice per group. Results are representative of 2 separate experiments.