Figure 6.
Inhibition of PHSRN-induced α5β1 and MMP-1 up-regulation, and PHSRN-induced invasion by α5 silencing. (A) Fluorescence quantitation of HMVEC, expressing either α5 or nonspecific control (NC) siRNA. X-axis, treatments; black bars, α5 siRNA; gray bars, NC siRNA; Y-axis, mean expression levels (±SD). (B) Effects of PHSRN peptide treatment on invasion by HMVEC expressing either α5 or NC siRNA. X-axis, treatments; Y-axis, mean invasion percentages (±SD).