Figure 5.

A, Principle of deconvolution analysis to decompose a hormone concentration peak (top) into an underlying secretory burst of finite mass and shape, basal secretion, an exponential elimination process, and random (stochastic) effects (bottom, left to right). B, One step in the interactive process of repeatedly estimating pulse amplitudes (continuous line) and hormone half-life (interrupted line) simultaneously to fit hormone data shown by the asterisks. Arrows depict putative pulse-onset times.