Table 2.
Conditions associated with high uric acid levels
| Gender /age | Adult men, postmenopausal women |
| Race | African-American, Polynesian, Maori |
| Cardiovascular condition | Hypertension, metabolic syndrome, cardiovascular disease, obesity, insulin resistance, nonalcoholic fatty liver, obstructive sleep apnea |
| Kidney | Renal failure |
| Pregnancy | Preeclampsia |
| Diet | High purine meats, fructose, high-fat diets, beer |
| Habits | Acute exercise |
| Toxins | Lead (low dose) |
| Drugs | Calcineurin inhibitors, diuretics, pyrazinamide, ethambutol, low-dose aspirin, niacin, some HIV medications |
| Catabolic states | Leukemia, tumor lysis, polycythemia vera, postbariatric surgery, starvation, psoriasis |
| Ketosis | Diabetic ketoacidosis, starvation, high-fat diet |
| Lactate | Congestive heart failure, alcohol, Gaucher’s disease |
| Hereditary | Lesch Nyhan syndrome, increased phosphoribosylpyrophosphate synthetase, familial juvenile hyperuricemic nephropathy |
| Other | Down’s syndrome, hyperparathyroidism, hypothyroidism, sarcoidosis, emotional or physical stress, marathon running, high altitude |