TABLE 2.
Prevalence of the rs780094 at the GCKR gene, the −1131T→C at the APOA5 gene, and the 56C→G at the APOA5 gene single nucleotide polymorphisms in the different populations1
| Greece | Spain |
United States |
Singapore |
|||||
| Harokopio Study, general population | EPIGEM, general population | PREDIMED Valencia, high CVD risk | GOLDN Study, white non-Hispanics | BPR-CPHHD, Puerto Rican Hispanics | SNHS-98, Chinese | SNHS-98, Malays | SNHS-98, Asian Indians | |
| GCKR rs780094, CC/CT/TT (%) | 24/47/29 | 28/49/23 | 29/47/34 | 36/50/13 | 51/38/10 | 31/46/23 | 36/45/18 | 60/34/5 |
| APOA5 –1131T→C rs662799, TT/TC/CC (%) | 83/16/1 | 88/11/1 | 88/12/0.4 | 87/12/0.1 | 78/20/2 | 51/39/9 | 51/31/9 | 59/36/5 |
| APOA5 56C→G rs3135506, CC,CG,GG (%) | 87/12/1 | 89/10/1 | 87/12.5/0.2 | 89/10/0.4 | 81/18/1 | 99.7/0.2/0 | 96.3/3.37/0 | 94/5.6/0.2 |
1
EPIGEM, Epidemiología Genética y Molecular; PREDIMED, Prevención con Dieta Mediterránea; GOLDN, Genetics of Lipid Lowering Drugs and Diet Network; BPR-CPHHD, Boston Puerto Rican Health Study–Centers on Population Health and Health Disparities; SNHS-98, Singapore National Health Survey of 1998; CVD, cardiovascular disease. Genotype error rate was <1%.