Table 3.

Relative Levels of Numerical and Structural Chromosomal Instability in 10 OSs.

No.	Numerical Aberration		Structural Aberration of Chromosome 8			Type of CIN for Chromosome 8
	Overall Ploidy*	cen(8)	RECQL4 Copy Number	MYC Copy Number	Pattern of RECQL4 and MYC FISH Signals
OS1	Diploid	2	2	3	Not rearranged	—
OS4	Diploid	2	2	2	Not rearranged	—
OS5	Near-triploid	4	4	4	Not rearranged	N-CIN
OS7	Near-triploid	3	3	3	Not rearranged	N-CIN
OS9	Polyploid (>5n)	5	4	4	Scattered	S- and N-CIN
OS11	Diploid	4	6	4	Scattered	S- and N-CIN
OS12	Near-tetraploid	2	3	2	Scattered	S-CIN
OS13	Diploid	2	6	6	Scattered	S-CIN
OS15	Near-tetraploid	4	8	5	Scattered	S- and N-CIN
OS18	Near-triploid	3	5	3	Scattered	S- and N-CIN

CIN indicates chromosomal instability; N-CIN, numerical chromosomal instability; S-CIN, structural chromosomal instability.

^*The overall ploidy has been estimated by the enumeration of cen(3), cen(7), and cen(17) (Table W2) as described in the Materials and Methods section.