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. 2009 Feb 6;5(2):e1000291. doi: 10.1371/journal.ppat.1000291

Table 2. Immunohistological Evaluation of Liver Sections.

Mouse Fata Balloonb Gradec Stagec FASd LABe Caspased Tunelf
Naive:
 005 0 0 0(P0 L0) 0 2 0.2 0 3±2
 963 2 1 0(P0 L0) 0 1 0 0 8±3
 992 3 0 2(P0 L2) 0 3 0 2 m 8±3
 996 2 0 2(P0 L2) 0 2 0 2 m 11±2
986-AAA 2 2 3(P0 L3) 0 3 0 0 10±4
638-1a Patient serum 0 3 2(P0 L2) 0 4 0.4 2 m 18±2
985-RNA 3 3 3(P0 L3) 0 3 1.6 3 m, h 50±14
975-RNA 2 3 3(P0 L3) 0 4 4 3 m, h 26±13
990-H77c serum 3 2 2(P0 L2) 0 4 0.4 2 m 50±13
a

The degree of fatty change was scored as 0 (<5%), 1 (6–33%), 2 (34–66%) 3 (>66%).

b

Hepatocyte ballooning was scored on a scale of 0–4 where 0 is none and 4 is many.

c

Grade and Stage were scored using the Batts and Ludwig criteria.

d

FAS and caspase staining was scored semi-quantitatively where 0 = none, 1 = focal weak, 2 = diffuse weak; 3 = diffuse weak and focal strong; 4 = diffuse strong. For caspase staining, m is macrophages and h is hepatocytes.

e

The lobular apoptotic body count is an average of 5 fields counted at magnification ×100.

f

The number of Tunel positive nuclei is an average of 15 fields at magnification ×200.