Figure 5.
Representative currents recorded from GFP-positive hair cells exposed to 4.3 × 108 particles/ml of Ad1-VgRXR and 7 × 109 particles/ml of Ad1-ecd-hKCNQ4-G285S. A, A family of currents recorded from a type II hair cell excised at P4 and maintained in culture for 4 d. B, A family of currents recorded from a type I hair cell excised at P7 and maintained in culture for 2 d. C, Activation curves generated from the data shown in A and B and fitted with Boltzmann relations that had the following fit parameters: type II (circles), V(1/2), −39 mV; s, 6.8 mV; Gmax, 17 nS; type I (squares), V(1/2), −31 mV; s, 6.5 mV; Gmax, 4.8 nS.