Table 2.

Multivariate analysis of various prognostic factors in patients with NSCLC

	Univariate	Multivariate
Prognostic factor	P value	β	P value	Relative Risk (95%) CI)
ptLVD (high/low)	0.0001	0.828	0.003	2.288 (1.182–4.428)
Pathologic stage(I+II/III+IV)	0.0000	1.310	0.003	3.708 (1.581–8.694)
Pathologic N stage (N0/N2–3)	0.0000	1.218	0.010	3.382 (1.344–8.511)
LVI (-/+)	0.0002	0.714	0.052	2.041 (0.993–4.196)
VEGF-C(-/+)	0.0054	-0.365	0.490	0.694 (0.246–1.958)
Ki67%	0.0012	0.726	0.032	2.067 (1.026–4.161)

(LVI: lymphatic vessel invasion, ptLVD: peritumoral lymphatic vessel density, Ki67/%: Ki-67 index of the endothelium cells of the micro lymphatic vessels)