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Transmission electron micrograph of high-pressure frozen and cryosubstituted cell of Verrucomicrobium spinosum, immunogold labelled using anti-double-stranded DNA mouse monoclonal antibody and goat anti-mouse IgG bound to 10-nm-colloidal gold, showing labelling only over the condensed fibrillar nucleoid (white arrowheads) which is contained within a pirellulosome bounded by an intracytoplasmic membrane (ICM). Bar – 500 nm.
