Fig. 4.

Detection of Anti-PA antibodies. After the vaccination regime, sera were derived from each group of mice just before and after challenge with B. anthracis Sterne for assays of anti-PA antibodies (A) and the anti-toxin neutralizing antibodies (B). Each triangle or diamond represents the value of anti-PA antibody detected in the serum of each individual mouse. The antibody responses for the control mice and those treated with NCK1895 (empty vector) were below the detection limit. For some of the mice vaccinated with DC-pep or Ctrlpep, IgG levels were below the detection limits, and these values were not recorded on the figure. Each symbol of each value represents the serum derived from each mouse. All data are representative of 2 independent experiments.