Figure 7.
Facilitation of sexually receptive and proceptive behaviors in ovariectomized rats treated with 17-β estradiol benzoate (10 µg) once every four days followed by free estradiol (50 µg) on injection 4. A near maximal LQ score and a low levels of proceptive behaviors (e.g., ear wiggling, darts, and hops) were seen following the third treatment with EB (injection 3). Animals treated with free estradiol (50 µg) four hours before testing reached maximal receptivity and high proceptive behavior (injection 4). The LQ was significantly higher after injections 3 and 4 compared to injection 2 (repeated measures ANOVA; p < 0.05). Proceptive behavior was significantly higher by the injection 4 compared with tests 2 and 3 (Friedman repeated measures ANOVA on Ranks; p < 0.05). Data are means ± SEM of 12 animals. * p < 0.05 significantly greater than proceptive scale score for injections 2 and 3 (Dunnett’s post hoc). † p < 0.05 versus LQ for injection 2 (Newman-Keuls post hoc).