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. 2006 May 11;174(3):349–355. doi: 10.1164/rccm.200604-472OC

TABLE 1.

INCIDENCE OF TUBERCULIN SKIN TEST AND QUANTIFERON-TB GOLD IN-TUBE ASSAY CONVERSIONS OVER A 18-MONTH PERIOD AMONG PARTICIPANTS WHO WERE CONCORDANTLY NEGATIVE BY BOTH TESTS AT BASELINE*

Definition of Conversion No. Serially Tested No. of Conversions % Incidence of Conversions (95% CI)
TST
 1. Baseline induration of < 10 mm and follow-up TST of ⩾ 10 mm, with increment of ⩾ 6 mm 147 14 9.5 (5.3–15.5)
 2. Baseline induration of < 10 mm and follow-up TST of ⩾ 10 mm, with increment of ⩾ 10 mm 147 6 4.1 (1.5–8.7)
QFT
 3. Baseline IFN-γ < 0.35 IU/ml and follow-up IFN-γ ⩾ 0.35 IU/ml 147 17 11.6 (6.9–17.9)
 4. Baseline IFN-γ < 0.35 IU/ml and follow-up IFN-γ ⩾ 0.70 IU/ml 147 11 7.5 (3.8–13.0)
Combinations of TST and QFT
 1 or 3 147 22 14.9 (9.6–21.8)
 2 or 4 147 11 7.5 (3.8–13.0)
 1 and 3 147 9 6.1 (2.8–11.3)
 2 and 4 147 6 4.1 (1.5–8.7)

Definition of abbreviations: CI = confidence interval; QFT = QuantiFERON-TB Gold In-Tube assay; TST = tuberculin skin test.

*

n = 147.