TABLE 1.
CHARACTERISTICS OF STUDY POPULATION
| Nontransplant Normal (n = 10) | Transplant Normal (n = 16) | Acute Rejection (n = 10) | CMV (n = 9) | Bronchitis (n = 12) | p Value | |
|---|---|---|---|---|---|---|
| Female, n (%) | 8 (80) | 6 (38) | 4 (40) | 4 (44) | 7 (58) | 0.25 |
| Age at transplantation, yr (mean ± SD) | 34.3 ± 8.7 | 48.6 ± 13.6 | 45.3 ± 17.5 | 55.0 ± 14.5 | 45.3 ± 17.5 | 0.07 |
| Pretransplantation disease, n (%) | 0.15 | |||||
| COPD/α1-AT | 8 (50) | 7 (70) | 4 (44) | 3 (25) | ||
| CF/bronchiectasis | 5 (31) | 3 (30) | 2 (22) | 8 (66) | ||
| Other | 3 (19) | 3 (33) | 1 (8) | |||
| Type of transplant, n (%) | 0.56 | |||||
| Single | 1 (6) | 1 (11) | 1 (8) | |||
| Bilateral | 15 (94) | 10 (100) | 8 (89) | 11 (92) | ||
| FEV1 at bronchoscopy, L (mean ± SD) | 3.37 ± 1.13 | 2.80 ± 0.87 | 2.43 ± 0.96 | 2.39 ± 0.98 | 2.16 ± 0.78 | 0.07 |
| Time from transplantation to bronchoscopy, d, median (interquartile range) | 182 (55–502) | 76 (46–109) | 88 (57–255) | 226 (54–723) | 0.21 |
Definition of abbreviations: α1-AT = α1-antitrypsin deficiency; CF = cystic fibrosis; CMV = cytomegalovirus; COPD = chronic obstructive pulmonary disease.