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. Author manuscript; available in PMC: 2009 Feb 26.
Published in final edited form as: Brain Res. 2006 Oct 3;1119(1):26–39. doi: 10.1016/j.brainres.2006.08.078

Fig. 5. ΔRR has a wide therapeutic window.

Fig. 5

OHC were infected with ΔRR (105 pfu) on day −2, 0, +1, or +2 relative to initiation of KA treatment. Infection on day −2 indicates virus was added 2 days prior to KA treatment, while infection on day +2 signifies virus was added 2 days after KA treatment. Staining with ethidium homodimer was done on day +3 for all cultures and the data are expressed as % dead cells ± SEM. Neuroprotection was calculated as described in materials and methods relative to background cell death at the time of ΔRR infection and shown in Fig. 3A.