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Comparison of sequences of four PRPs shows major differences in the region including residue 115, which was demonstrated previously to be involved in gyrase protection for quinolones. An alignment of MfpA (29), MfpAMt (Rv 3361c), QnrB4 (AAZ04784), and VPA0085 is shown. Conserved residues in the four sequences are in black, and those in three sequences are in light gray. C115 is indicated.
