TABLE 4.
uvrD303 suppresses the constitutive SOS phenotype of recA730 cells by a mechanism that is dependent on the UvrD303 C terminus
| Strain | uvrD | recA | Avg RI ±SD | % Constitutivea ± SD |
|---|---|---|---|---|
| SS996 | + | + | 1.00 | 0.3 ± 0.5 |
| SS5704 | 303 | + | 1.2 ± 0.6 | 0.7 ± 1.5 |
| SS4629 | + | 730 | 39.2 ± 3.3 | 93.7 ± 11.0 |
| SS5801 | 303 | 730 | 1.1 ± 0.1 | 0.6 ± 0.3 |
| SS5990 | 701 | 730 | 43.8 ± 2.1 | 99.1 ± 0.8 |
| SS5989 | 303, 701 | 730 | 43.6 ± 2.5 | 99.2 ± 0.5 |
| SS4976 | + | 4142b | 17.1 ± 2.4 | 99.3 ± 0.9 |
| SS5809 | 303 | 4142b | 17.5 ± 3.8 | 98.4 ± 1.0 |
a
Percentage of cells with an RI sixfold or more greater than the average RI of the wild-type strain (± standard deviation).
b
All strains containing recA4142 also have the recAo1403 operator mutation, which increases the percentage of the population that displays constitutive SOS activity from about 15% to nearly all of the cells (27a).