FIG. 2.

The ApbC/Nbp35 family of iron-sulfur proteins evolved before the Archaea and Eukarya diverged. This phylogeny was inferred using a protein maximum-likelihood method, although a neighbor-joining distance method produced a similar tree. Bootstrap values from the neighbor-joining consensus tree are shown near branches supported by a plurality of 100 trees. Numbers in parentheses after some species names differentiate paralogs from the same genome. Asterisks indicate sequences with amino-terminal ferredoxin-like domains. The complete organism names and accession numbers are listed in the supplemental material. Bar, 0.1 amino acid substitution expected per site.