TABLE 1.
HPV E7 expression does not affect mitosis as determined by time-lapse videomicroscopy
| RPE1 cells or MEFsa | Number of cells | Length of mitosis (min) | Length of cytokinesis (min) | Length of mitosis + cytokinesis (min) |
|---|---|---|---|---|
| RPE1 cells | ||||
| RPE1-vector | 56 | 34 ± 7 | 96 ± 28 | 128 ± 30 |
| RPE1-E7 | 17 | 37 ± 6 | 102 ± 39 | 138 ± 40 |
| MEFs | ||||
| Wild-type MEFs | 40 | 41 ± 11 | 33 ± 16 | 74 ± 17 |
| Rb−/− MEFs | 40 | 44 ± 15 | 45 ± 27 | 89 ± 38 |
a
For RPE1 cells, P values of 0.19, 0.66, and 0.54 for time spent in mitosis, cytokinesis, and mitosis plus cytokinesis, respectively, are considered significant. For MEFs, P values of 0.40, 0.01, and 0.03 for time spent in mitosis, cytokinesis, and mitosis plus cytokinesis, respectively, are considered significant.