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. Author manuscript; available in PMC: 2009 Feb 26.
Published in final edited form as: J Control Release. 2006 Mar 10;112(1):120–128. doi: 10.1016/j.jconrel.2006.01.013

Table 1.

Properties of microspheres used for intramuscular delivery

PLG i.v. a Mean molecular weight b DNA loading in PLG microspheres Mass of PLG microspheres injected
Mean diameter
50 μg DNA 20 μg DNA
High MW 0.6–0.8 dl/g 113 kDa 5.4 μg/mg 9.3 mg – 2.8±1.6 μm
Low MW 0.16–0.24 dl/g 12 kDa 4.6 μ/mg 10.9 mg 4.4 mg 3.5±2.1 μm
a

Inherent viscosity.

b

Weight average molecular weight (MW). The number was provided by the supplier.