Table 2.
Cognitive Testing at First Evaluation
| LPA N=4 | PNFA N=6 | SD N=5 | P | |
|---|---|---|---|---|
| MMSE (30) | 22.0 (17 – 25) | 27.0 (23 – 30) | 21.0 (15 – 29) | 0.052 |
| Language | ||||
| WAB Fluency (10) | 9.0 (5 – 9) | 9.0 (2 – 9) | 9.0 (8 – 10) | 0.30 |
| Motor Speech Evaluation | ||||
| Apraxia of Speech (0=none – 7=severe) | 0.0 (0 – 0) | 1.5 (0 – 6) | 0.0 (0 – 0) | 0.03 |
| Dysarthria (0=none – 7=severe) | 0.0 (0 – 0) | 2.0 (0 – 4) | 0.0 (0 – 0) | 0.03 |
| Boston Naming Test (15) | 13.0 (11 – 14) | 13.5 (6 – 15) | 2.0 (2 – 3) | 0.01 |
| Verbal Fluency | ||||
| Animals/min | 10.5 (8 – 16) | 10.0 (0 – 22) | 4.0 (1 – 7) | 0.05 |
| ‘D’ words/min | 7.0 (5 – 18) | 4.0 (3 – 13) | 6.0 (1 – 9) | 0.31 |
| Word and object knowledge | ||||
| WAB Auditory Word Recognition (60) | 57.0 (52 – 60) | 60.0 (59 – 60) | 51.0 (36 – 59) | 0.02 |
| PPT Pictures (52) | 51.0 (47 – 52) | 49.0 (40 – 52)* | 35.0 (31 – 48) | 0.03 |
| WAB Repetition (100) | 75.0 (74 – 80) | 97.0 (74 – 100) | 90.5 (73 – 99)* | 0.17 |
| Syntactic Comprehension | ||||
| WAB Sequential Commands (80) | 63.0 (37 – 68) | 76.0 (63 – 80) | 69.0 (66 – 80)* | 0.10 |
| CYCLE (2=simplest, 9=most complex) | ||||
| CYCLE 2, 3 (10) | 10.0 (8 – 10) | 10.0 (10 – 10) | 10.0 (9 – 10) | 0.46 |
| CYCLE 4 (15) | 14.5 (6 – 15) | 15.0 (10 – 15) | 15.0 (14 – 15) | 0.56 |
| CYCLE 5, 7 (10) | 6.5 (3 – 9) | 9.5 (4 – 10) | 10.0 (5 – 10) | 0.15 |
| CYCLE 8 (10) | 6.0 (4 – 9) | 10.0 (5 – 10) | 10.0 (9 – 10) | 0.04 |
| CYCLE 9 (10) | 4.0 (2 – 7) | 7.5 (3 – 10) | 9.0 (6 – 10) | 0.15 |
| Memory | ||||
| CVLT-SF Total Learning (36) | 22.0 (9 – 22)* | 26.0 (14 – 29)* | 9.0 (2 – 19) | 0.054 |
| CVLT-SF 10 minute Recall (9) | 5.0 (0 – 5)* | 8.0 (1 – 8)* | 1.0 (0 – 5) | 0.06 |
| CVLT-SF Recognition (9) | 9.0 (8 – 9)* | 9.0 (8 – 9)* | 7.0 (0 – 8) | 0.02 |
| Modified Rey Figure Recall (17) | 6.5 (3 – 15) | 6.5 (0 – 13) | 7.0 (0 – 13) | 0.83 |
| Executive Function | ||||
| Modified Trails Time (120) | 120.0 (73 – 120) | 97.0 (21 – 120) | 53.0 (36 – 120) | 0.48 |
| Modified Trails # of Correct Lines (14) | 10.5 (0 – 14) | 11.0 (3 – 14) | 14.0 (3 – 14) | 0.36 |
| Calculations (5) | 3.0 (1 – 5) | 5.0 (2 – 5) | 5.0 (0 – 5) | 0.38 |
| Modified Rey Figure Copy (17) | 15.5 (13 – 17) | 16.0 (14 – 17) | 16.0 (12 – 17) | 0.83 |
| Mood & Personality | ||||
| Geriatric Depression Scale (30) | 4.0 (2 – 12) | 5.0 (2 – 28) | 10.0 (6 – 20) | 0.24 |
| Neuropsychiatric Inventory Total | 8.0 (2 – 23) | 8.0 (0 – 24)* | 16.0 (4 – 32) | 0.61 |
*
- One observation missing. Values are presented as medians (range). Highest possible test scores are shown in parentheses. LPA = logopenic aphasia; PNFA = progressive non-fluent aphasia; SD = semantic dementia; MMSE = Mini Mental State Exam; WAB = Western Aphasia Battery; PPT = pyramids and palm trees test; CYCLE = Curtiss-Yamada Comprehensive Language Evaluation; CVLT-SF = California Verbal Learning Test San Francisco.