Table 4.
Cognitive Profiles in PIB-Positive PPA and AD
| PIB-Pos PPA N = 6 | AD N=10 | P | |
|---|---|---|---|
| Age at PET | 61.2 (56.6 – 70.7) | 65.2 (52.5 – 78.3) | 0.26 |
| MMSE (30) | 23.5 (17 – 29) | 25.0 (10 – 28) | 0.79 |
| Language | |||
| Boston Naming Test | 11.5 (3 – 14) | 13.0 (2 – 15) | 0.37 |
| Animals/min | 7.0 (4 – 18) | 10.5 (2 – 18) | 0.18 |
| ‘D’ words/min | 9.5 (5 – 16) | 10.0 (2 – 22) | 0.71 |
| Memory | |||
| CVLT-SF Total Learning (36)* | 21.0 (9 – 22)* | 18.5 (6 – 25)** | 0.52 |
| CVLT-SF 10 minute Recall (9)** | 5.0 (0 – 7)* | 0.0 (0 – 5)* | 0.06 |
| CVLT-SF Recognition (9)** | 9.0 (8 – 9)* | 8.0 (5 – 9)* | 0.24 |
| Modified Rey Figure Recall (17) | 6.0 (3 – 15) | 1.0 (0 – 5) | 0.01 |
| Executive Function | |||
| Modified Trails Time (120) | 97.0 (53 – 120) | 120.0 (59 – 120)* | 0.61 |
| Modified Trails # of Correct Lines (14) | 12.5 (0 – 14) | 13.0 (2 – 14)* | 0.69 |
| Calculations (5) | 3.5 (1 – 5) | 4.0 (0 – 5) | 0.96 |
| Modified Rey Figure Copy (17) | 16.5 (13 – 17) | 14.0 (10 – 16) | 0.03 |
| Geriatric Depression Scale (30) | 8.0 (0 – 23) | 6.0 (2 – 24) | 0.88 |
*
- One observation missing.
**
- Two observations missing. Values are presented as medians (range). Highest possible test scores are shown in parentheses. MMSE = Mini Mental State Exam; CVLT-SF = California Verbal Learning Test San Francisco.