FIG. 4.

Alendronate prevents glucocorticoid-induced bone loss in both Cx43^fl/− and Cx43^ΔOb-Ot/− mice. Mice were treated as indicated in Fig. 3. Initial BMD was determined when the pellets were implanted and the final BMD at the time of death. The percent change in BMD was calculated. pred, prednisolone. ^a p < 0.05 by generalized linear models, n = 6–11 mice.