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. 2009 Feb 9;119(3):524–530. doi: 10.1172/JCI36703

Figure 4. Lack of AT1A protects mice from aorta damage.

Figure 4

(A and B) Representative images of aorta sections from wild-type mice (26 to 29 months old), showing fragmentation of lamina elastica along all the perimeter of the vessel wall (A) and intraparietal accumulation of foamy cells destroying layers of elastic tunica media (B). (C) Aorta section from Agtr1a–/– mice (26 to 30 months old) showing regular elastic lamina. Original magnification, ×20.