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. 2009 Feb 9;119(3):524–530. doi: 10.1172/JCI36703

Figure 7. Lack of AT1A is associated with increased levels of Nampt and Sirt3 in the kidney.

Figure 7

By real-time PCR, whole kidney expression of both Nampt and Sirt3 was increased in Agtr1a–/– (26 to 30 months old) with respect to wild-type (26 to 29 months old) mice. Renal expression of Sirt1 mRNA was comparable in the 2 strains. Data are mean ± SD of 4 animals. *P < 0.05 versus wild-type by ANOVA corrected with Bonferroni coefficient.