Table 1.
Results of the samples to profiles classification. 1,464 samples from healthy tissues and cells including 15,931 genes from 35 anatomical classes were classified. Anatomical classes, number of samples and number of different array generations within each of the classes are listed in the table. The percentages of correctly classified samples are calculated with each normalization method.
# samples | # array gens | MAS | Z | HK | Q | WBL | MASAGC | ZAGC | HKAGC | QAGC | WBLAGC | |
TOTAL | 1464 | 5 | 74.2% | 77.9% | 75.5% | 77.6% | 76.1% | 86.7% | 89.6% | 89.7% | 89.8% | 89.3% |
Aorta | 24 | 1 | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% |
Bronchus | 94 | 2 | 81.9% | 81.9% | 81.9% | 81.9% | 81.9% | 86.2% | 86.2% | 86.2% | 86.2% | 86.2% |
Lung | 117 | 4 | 47.9% | 46.2% | 46.2% | 46.2% | 46.2% | 91.5% | 88.0% | 89.7% | 86.3% | 83.8% |
Alveolus | 34 | 1 | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% |
Bone marrow | 104 | 3 | 53.8% | 53.8% | 53.8% | 52.9% | 52.9% | 86.5% | 84.6% | 86.5% | 85.6% | 86.5% |
Peripheral blood | 260 | 3 | 53.1% | 70.8% | 61.2% | 70.8% | 61.2% | 62.7% | 82.3% | 82.3% | 83.5% | 82.3% |
Tonsil | 16 | 2 | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% |
Colon | 18 | 3 | 88.9% | 88.9% | 88.9% | 88.9% | 88.9% | 88.9% | 94.4% | 88.9% | 94.4% | 88.9% |
Liver | 12 | 3 | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% |
Pancreas | 21 | 4 | 76.2% | 81.0% | 81.0% | 76.2% | 81.0% | 95.2% | 95.2% | 95.2% | 95.2% | 95.2% |
Kidney | 49 | 3 | 73.5% | 75.5% | 73.5% | 73.5% | 75.5% | 89.8% | 87.8% | 89.8% | 87.8% | 87.8% |
Testis | 13 | 3 | 92.3% | 92.3% | 92.3% | 92.3% | 92.3% | 92.3% | 92.3% | 92.3% | 92.3% | 92.3% |
Prostate | 70 | 4 | 80.0% | 75.7% | 80.0% | 75.7% | 75.7% | 98.6% | 95.7% | 98.6% | 95.7% | 95.7% |
Foreskin | 30 | 2 | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% |
Ovary | 14 | 2 | 57.1% | 64.3% | 57.1% | 64.3% | 57.1% | 78.6% | 78.6% | 78.6% | 78.6% | 78.6% |
Uterus | 12 | 3 | 83.3% | 75.0% | 83.3% | 75.0% | 83.3% | 100% | 91.7% | 100% | 91.7% | 91.7% |
Endometrium | 12 | 1 | 50.0% | 83.3% | 50.0% | 66.7% | 83.3% | 100% | 100% | 100% | 100% | 100% |
Placenta | 28 | 3 | 67.9% | 67.9% | 64.3% | 67.9% | 67.9% | 82.1% | 75.0% | 75.0% | 75.0% | 75.0% |
Breast | 25 | 4 | 64.0% | 64.0% | 64.0% | 64.0% | 64.0% | 84.0% | 96.0% | 84.0% | 96.0% | 100% |
Thyroid | 16 | 2 | 87.5% | 100% | 88% | 100% | 100% | 100% | 93.8% | 93.8% | 93.8% | 87.5% |
Thymus | 12 | 2 | 66.7% | 75.0% | 75.0% | 75.0% | 75.0% | 83.3% | 75.0% | 83.3% | 83.3% | 83.3% |
Muscle | 11 | 2 | 90.9% | 100% | 90.9% | 100% | 100% | 54.5% | 54.5% | 54.5% | 54.5% | 54.5% |
Skin cuticle | 85 | 3 | 91.8% | 91.8% | 91.8% | 91.8% | 91.8% | 96.5% | 97.6% | 97.6% | 97.6% | 97.6% |
Brain | 35 | 3 | 54.3% | 60.0% | 54.3% | 60.0% | 60.0% | 88.6% | 88.6% | 85.7% | 85.7% | 85.7% |
Cerebral cortex | 34 | 1 | 55.9% | 61.8% | 55.9% | 61.8% | 58.8% | 58.8% | 61.8% | 52.9% | 61.8% | 58.8% |
Frontal lobe | 33 | 1 | 93.9% | 93.9% | 93.9% | 93.9% | 93.9% | 93.9% | 93.9% | 93.9% | 93.9% | 93.9% |
Hypothalamus | 25 | 1 | 100% | 100% | 100% | 100% | 100% | 100% | 96.0% | 96.0% | 96.0% | 96.0% |
Cerebellum | 33 | 2 | 84.8% | 84.8% | 84.8% | 84.8% | 84.8% | 97.0% | 97.0% | 97.0% | 97.0% | 97.0% |
Lens | 11 | 1 | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 90.9% | 100% | 100% |
Optic nerve | 44 | 1 | 93.2% | 93.2% | 93.2% | 93.2% | 93.2% | 93.2% | 93.2% | 93.2% | 93.2% | 93.2% |
Striated skeletal muscle | 92 | 2 | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% |
Umbilical vein | 38 | 1 | 97.4% | 97.4% | 97.4% | 97.4% | 97.4% | 97.4% | 97.4% | 97.4% | 97.4% | 97.4% |
Intervertebral disc | 11 | 1 | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% | 100% |
Ventricle myocardium | 18 | 2 | 61.1% | 61.1% | 61.1% | 61.1% | 61.1% | 100% | 100% | 100% | 100% | 100% |
Atrium myocardium | 13 | 1 | 100% | 100% | 100% | 100% | 100% | 76.9% | 76.9% | 84.6% | 76.9% | 76.9% |