Skip to main content
. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2009 Jan;15(1):1–11. doi: 10.1016/j.bbmt.2008.10.026

Table 2.

T cell, B cell, and granulocyte engraftment in blood in B6 mArt-/- mice following congenic and allogeneic transplants.

BMT Marrow Prep and Pre-condition 1 Month Post-HSCT 2 Months Post-HSCT At least 3 Months Post-HSCT
T cells, %* B cells, %* T cells, %* B cells, %* T cells, %* B cells, %* Granulocytes, %
Congenic (CD45.1) HSC (n=6) 4.0±2.7 0 16.3±4.1 0 64.4±8.2 0 N/A
Congenic (CD45.1) HSC/TBI (n=4) 44.6±3.5 18.4±2.8 56.6±4.5 23.5±7.0 46.1±2.2 35.2±2.1 64.1±11.2
Allogeneic (BALB/c) HSC (n=5) 0 0 0 0 not available not available not available
Allogeneic (BALB/c) HSC/TBI (n=4) 1.8±1.2(3)£ 3.3±1.5(3)£ 4.4±3.4(2)£ 3.4±0.7(2)£ not available not available not available

WT mice used as controls had a mean percent of 28.5±17.7 CD3+ (T cells) and a mean percent of 37.5 ± 2.1 CD45R/B220+ (B cells) in the CD45+ lymphocyte gate.

*

Mean percent of CD3+ (T cells) or CD45R/B220+ (B cells) in CD45+ lymphocyte gate ± standard deviation.

Mean percent of donor granulocytes of total granulocytes ± standard deviation.

For HSC (linc-kit+), 1 × 105 cells were injected. Mice treated with TBI (Total Body Irradiation) received 3Gy.

£

Mean±SD of engrafted animals. ( ) = the number of transplanted mice that engrafted (≥0.75% donor cells).