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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Exp Gerontol. 2008 Aug 26;43(12):1102–1107. doi: 10.1016/j.exger.2008.08.047

Table 3.

Percentage of variation of bilirubin concentrations explained by classical factors and the −53(TA-repeat) and the T-3279G polymorphism (assuming a recessive genetic model). Values given are the r2 values (as percentage) from linear regression with various adjustments.

r2 (%) full model a r2 (%) submodel b r2 (%) explained by polymorphisms c
53(TA-repeat) polymorphism
 Cases 24.1 8.7 15.4
 Controls 23.6 10.5 13.1
SNP T-3279G
 Cases 17.9 8.7 9.2
 Controls 17.0 10.5 6.5
53(TA-repeat) polymorphism and SNP T-3279G combined
 Cases 24.1 8.7 15.4
 Controls 24.1 10.5 13.6
a

adjusted for age, gender, smoking status, and either of the two polymorphisms or the two polymorphisms combined;

b

same as a but without adjustment for any polymorphism;

c

The variation explained by the polymorphisms was calculated by the difference of r2 between a full model a and the submodel b.