Table 3.
Percentage of variation of bilirubin concentrations explained by classical factors and the −53(TA-repeat) and the T-3279G polymorphism (assuming a recessive genetic model). Values given are the r2 values (as percentage) from linear regression with various adjustments.
| r2 (%) full model a | r2 (%) submodel b | r2 (%) explained by polymorphisms c | |
|---|---|---|---|
| −53(TA-repeat) polymorphism | |||
| Cases | 24.1 | 8.7 | 15.4 |
| Controls | 23.6 | 10.5 | 13.1 |
| SNP T-3279G | |||
| Cases | 17.9 | 8.7 | 9.2 |
| Controls | 17.0 | 10.5 | 6.5 |
| −53(TA-repeat) polymorphism and SNP T-3279G combined | |||
| Cases | 24.1 | 8.7 | 15.4 |
| Controls | 24.1 | 10.5 | 13.6 |
adjusted for age, gender, smoking status, and either of the two polymorphisms or the two polymorphisms combined;
same as a but without adjustment for any polymorphism;
The variation explained by the polymorphisms was calculated by the difference of r2 between a full model a and the submodel b.