Table 4.

Logistic regression analysis adjusted for age and stratified for gender investigating the association of bilirubin concentrations and the −53(TA-repeat) and the T-3279G polymorphisms (genotypes) on the change of odds for coronary artery disease (CAD). Values given are the odds ratio (OR), 95% confidence intervals (CI), and the respective p-value testing for deviance of the OR from unity.

	Women		Men
	OR (95% CI)	P value	OR (95% CI) P value	P value
Bilirubin (increment 0.1mg/dl)
Model 1 a	0.77(0.68–0.87)	3.2×10−5	0.90(0.86–0.94)	2.6×10−6
Model 2 b	0.72(0.61–0.85)	0.0002	0.93(0.88–0.98)	0.005
Model 3 c	0.79(0.66–0.94)	0.009	0.94(0.89–0.99)	0.018
−53(TA-repeat) polymorphism
Additive model (per copy of 7 repeats)	0.85(0.60–1.21)	0.37	1.06(0.86–1.31)	0.59
Recessive model (7/7 vs. 6/6+6/7)	0.93(0.45–1.93)	0.84	0.97(0.61–1.54)	0.90
SNP T-3279G
Additive model (per copy of G)	0.95(0.68–1.33)	0.76	1.04(0.85–1.27)	0.71
Recessive model (G/G vs. T/T+T/G)	0.92(0.52–1.62)	0.78	0.88(0.61–1.28)	0.51

^aadjusted for age

^badjusted for age, LDL cholesterol, HDL cholesterol, BMI, smoking, serum creatinine

^cas in ^b, but additionally adjusted for glucose and albumin