Table 1.
Demographic information in this study. Key: CON --- healthy controls without an apoE E4, DEP ---depressed patients without an apoE E4, E4 DEP ---depressed patients with one apoE E4.
| CON N = 31 | DEP N = 38 | E4 DEP N = 14 | Test Statistic | p value | |
|---|---|---|---|---|---|
| Age | 68.9 (5.9) | 64.7 (4.5) | 68.8 (6.5) | F = 6.16 | 0.0032 |
| Sex (% Female) | 67.8% (21/31) | 71.1 % (27/38) | 50.0% (7/14) | χ2 = 1.99 | 0.3690 |
| MMSE | 28.7 (1.7) | 28.9 (1.6) | 27.9 (1.9) | F = 1.56 | 0.2163 |
| MADRS | - | 14.9 (11.1) | 16.9 (10.7) | t = 0.56 | 0.5759 |
| Antidepressant Use | - | 92.1% (35/38) | 85.7% (12/14) | Fisher’s exact test | 0.6024 |
| Brain volume (cm3) | 1547.7 (161.7) | 1548.5 (161.2) | 1520.7 (162.9) | F = 0.17 | 0.8462 |