Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Mar 6;4(3):e4728. doi: 10.1371/journal.pone.0004728

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Almendro et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

A) Immunofluorescence (IF) staining of MMP7 in the non-resistant (HT29, HCT116 p53^+/+, HCT116 p53^−/−) and resistant cells (RHT29, RHCT116 p53^+/+, RHCT116 p53^−/−). MMP7 is strongly upregulated in the RHT29 and RHCT116 p53^−/− cell lines and its expression is also increased by oxaliplatin treatment. Levels of MMP7 were also analyzed by qPCR both in vitro (B) and in vivo (C) obtaining a similar pattern than in the IF assay. Results represent the mean±SEM for 6 samples in each group. Values that are significantly different between control and treated group by ANOVA analysis are indicated by *p<0.05,**p<0.001,***p<0.0001, and between different cell lines †††p<0.0001. OXA: oxaliplatin.