Table 2.
The empirical coverage levels and average lengths of 95% CIs for RD obtained based on (i) the MH-0 method, (ii) the MH-0.5 method, and (iii) the new exact method for cases with extremely to moderately low event rates. The results are based on 1000 simulated data sets consisting of 48 2 × 2 tables with the observed sample sizes listed in Table 1
| Empirical coverage level (average length × 1000) | |||||||
| (a) pc ∼ U(0, 0.01%) |
(b) pc ∼ U(0, 10%) |
||||||
| RD | MH-0 | MH-0.5 | Exact | RD | MH-0 | MH-0.5 | Exact |
| 0 | 0.761 (0.29) | 1.000 (2.10) | 1.000 (1.45) | 0. | 0.959 (10.3) | 0.959 (10.3) | 0.995 (12.3) |
| 0.01% | 0.896 (0.44) | 1.000 (2.13) | 1.000 (1.51) | 5% | 0.947 (12.2) | 0.947 (12.2) | 0.959 (14.8) |
| 0.05% | 0.930 (0.78) | 0.999 (2.22) | 0.999 (1.91) | 10% | 0.957 (13.7) | 0.957 (13.7) | 0.958 (16.8) |
| 0.50% | 0.955 (2.28) | 0.998 (3.69) | 0.987 (3.67) | ||||