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. 2008 Dec 8;10(2):352–363. doi: 10.1093/biostatistics/kxn042

Table 1.

Bias and standard deviation (shown in brackets) in estimating μ for the 4 estimation methods in 9 different scenarios. The true values of α and σ in each scenario are shown in the first 2 columns, and μ = 100 for all scenarios. All values are given to 2 significant figures

σ α MLE Saddle RMA-75 RMA
5 102 0.0079 (0.22) – 0.25 (0.22) 1.7 (1.6) 12 (2.7)
20 102 0.0024 (0.47) 0.013 (0.50) 5.4 (2.3) 25 (2.6)
100 102 0.013 (1.6) 11.0 (1.5) 4.8 (11) 47 (9.0)
5 103 – 0.023 (0.67) – 0.37 (0.65) 4.2 (7.5) 44 (23)
20 103 – 0.025 (1.4) – 1.3 (1.4) 6.6 (11) 69 (24)
100 103 – 0.098 (3.1) – 3.4 (3.1) 26.0 (18) 170 (24)
5 104 0.022 (2.3) – 0.36 (2.2) 32.0 (64) 380 (230)
20 104 0.20 (4.2) – 1.3 (4.0) 32.0 (66) 390 (220)
100 104 0.069 (9.2) – 6.5 (9.0) 41.0 (85) 520 (240)