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. 2008 Dec 8;10(2):352–363. doi: 10.1093/biostatistics/kxn042

Table 2.

Bias and standard deviation (shown in brackets) in estimating σ for the 4 estimation methods in 9 different scenarios. The true values of α and σ in each scenario are shown in the first 2 columns, and μ = 100 for all scenarios. All values are given to 2 significant figures. ∞a and ∞b indicate, respectively, where 32.4% and 0.3% of replicates yielded infinite estimates

σ α MLE Saddle RMA-75 RMA
5 102 0.00059 (0.20) – 0.40 (0.19) 1.5 (0.71) 7.0 (1.9)
20 102 – 0.0069 (0.40) – 0.46 (0.43) 5.6 (1.0) 15.0 (1.6)
100 102 0.003 (1.0) 7.3 (0.99) 25.0 (5.0) 45.0 (5.1)
5 103 – 0.067 (0.62) – 0.56 (0.56) 3.2 (4.7) 32.0 (19)
20 103 – 0.11 (1.2) – 1.9 (1.1) 6.0 (5.3) 44.0 (19)
100 103 – 0.00048 (2.8) – 5.9 (2.7) 27.0 (7.8) 100.0 (16)
5 104 – 0.72 (2.4) – 1.2 (2.1) ∞a (∞a) 310.0 (190)
20 104 – 0.40 (4.0) – 2.5 (3.6) ∞b (∞b) 300.0 (180)
100 104 – 0.52 (8.5) – 10.0 (7.8) 36.0 (46) 360.0 (190)